Artificial Sweeteners

Warning: Long, science-heavy video. No funny cats or guys getting hit in the nuts. Artificial sweeteners, or as they are usually referred to in the literature “non-caloric” sweeteners or “high-intensity” sweeteners, address the problem of sugar calorie excess in our diet. They’ve been demonstrated to support weight loss or maintenance, reduce cavities and can be part of a healthy lifestyle. Much focus has been on CSPI report: I disagree with CSPI on about 25% of their rankings, but I appreciate that they take a very conservative stance. Citations: Aspartame: 1. Comp Funct Genomics. 2010. In vivo cytogenetic studies on aspartame. 2. Drug Chem Toxicol. 2004 Aug;27(3):257-68. Genotoxicity of aspartame. 3. Am J Ind Med. 2010 Dec;53(12):1197-206. Aspartame administered in feed, beginning prenatally through life span, induces cancers of the liver and lung in male Swiss mice. 4. Toxicol In Vitro. 2011 Feb;25(1):286-93. In vitro effect of aspartame in angiogenesis induction. Sucralose: 5. Regul Toxicol Pharmacol. 2009 Oct;55(1):1-5. An overview of the safety of sucralose. 6. Regul Toxicol Pharmacol. 2009 Oct;55(1):6-12. Expert panel report on a study of Splenda in male rats. 7. Food Chem Toxicol. 2000;38 Suppl 2:S53-69. Acute and subchronic toxicity of sucralose. 8. Food Chem Toxicol. 2000;38 Suppl 2:S71-89. A combined chronic toxicity/carcinogenicity study of sucralose in Sprague-Dawley rats. 9. Food Chem Toxicol. 2000;38 Suppl 2:S91-7. A carcinogenicity study of
Video Rating: 4 / 5


  1. bannor99 March 14, 2012 3:42 pm 

    If you want a low-cal sweetener that’s (apparently) safe, tasty and safe for you teeth, try erythritol. Unlike most of the polyols aka “sugar alchols”, it doesn’t have that? initial unpleasant laxative effect.

  2. Nextstopearth March 14, 2012 3:20 pm 

    So just to be clear, if one were going to take in a moderate amount of sugar per day, would you consider it a good idea to replace that sugar with an equivalent(in? sweetness) amount of artificial sweetener?

  3. C0nc0rdance March 14, 2012 2:38 pm 

    It looks like both are pretty safe in tight moderation (assuming you “burn what you take in”), but if you? are the type of person who gets even a little excess, I think you’d be better off with sucralose.

    I still have deep reservations about AceK, but it’s the LACK of evidence that I worry about.

  4. wjestick March 14, 2012 2:02 pm 

    These sweeteners have not been in food long enough to be declared safe. No evidence can mean have not looked. The problem with new additives is that in addition to the direct effects, there are many possible interactions, with the body and other additives.

    You can’t get to all that in a short video, but you should highlight that shortcoming in your analysis. As a result of that? omission, the video comes over a little like propaganda rather than a review of accepted research.

  5. C0nc0rdance March 14, 2012 1:45 pm 

    Here are some fun ways to date these:
    Saccharin is older than the phonograph.
    AceK is about as old as the first nuclear submarine.
    Aspartame is about as old as? the Beatles White Album.
    Sucralose is about as old as Star Wars.

  6. ryanswan0 March 14, 2012 1:21 pm 

    Thank you for making this video, I found it very informative. I stay away from artificial sweeteners because I can usually tell my digestive system is a bit off when I consume them, plus I don’t like the aftertastes.? But most importantly, I agree with your conclusion that fixing our diets, so as to not have the excessive sweetness craving, will benefit us greatly.

    Have you done any videos de-bunking the breakdown of aspartame into a neurotoxin at certain temperatures?

  7. unassumption March 14, 2012 1:11 pm 

    so we don’t know i star? wars or the photograph are safe yet :O

  8. wjestick March 14, 2012 12:53 pm 

    Are you? dumbing down my point?

  9. wjestick March 14, 2012 12:07 pm 

    I watched the video again and I was perhaps a little harsh. The conclusion was sensible advice even if some of the wording regarding the conclusions on saccharin and Aspartame were somewhat guarded.
    The nature is best argument was a little simplified, I’m sure everyone realises snake venom and poison frogs are bad.

    The dose argument regarding Aspartame overlooks the fact that it is used in a huge range of products and the quantity is? not controlled or listed on the packet.

  10. petecabrina March 14, 2012 11:55 am 

    Personally I do not know why anyone even bothers drinking soda or food laced with sweeteners or even sugar for that matter, a little occasionally is nice but peoples day to day dietary choices fail to astound me. Want evidence of the value of a paleo style diet have a look at Dr.Terry Wahls recent youtube video Minding Your Mitochondria relating to MS but which probably applies to many diseases/illnesses but also our day to day lifestyles. ?

  11. blade004 March 14, 2012 11:50 am 

    It’s very interesting? all this because i was at one point one of those guys who bought an Alkaline Water machine, thoughts that ALL artificial sweeteners were detrimental..etc.. the list goes on and on, so in a nutshell, i was a fucking idiot!. I bought into that “conspiracy” mentality by about 2005 which lasted until about 2009. It’s people like you Concordance that give us a hard does of “reality” and i have you and others to thank in giving us the real and logical facts. Thank you! :)

  12. IrwinJohnFinster March 14, 2012 11:40 am 

    Wow. Now *that* was surprising. So many people have brought up to me how ‘bad’ for you artificial sweeteners are, and Splenda always comes up as ‘one of the worst’. I listen to a professional talk about it, and it turns out? sucralose is pretty much the best option out of all of them. But the question still remains: does Splenda taste like candied rubber? 😛

    Oh and I agree that the solution isn’t to devise a lab generated super sweetener but for people to learn to just take in less sweeteners.

  13. RoScFan March 14, 2012 10:55 am 

    @C0nc0rdance can you make a video how these? things work? do they basically interact with receptors of the taste bud’s epithelia but are simply non-digestable lie cellulose?

  14. Ch4osW4rrior March 14, 2012 10:44 am 

    What are you’re personal views on the Paleo/Primal way of life/dieting? What are? your thoughts on grains?

  15. bsrk7 March 14, 2012 10:01 am 

    I’m extremely interested in the new findings that saccharine does not cause cancer in humans like it does in rats. Sassafras, once the principle ingredient in root beer among many other uses, was banned in the 70’s by the FDA for being slightly carcinogenic in lab rats. The industry has had to use artificial flavor in place of safrole ever since. I believe it’s time to revisit this issue of safrole. If we’re banning this? useful natural oil for no reason, it would be a real shame and a loss.

  16. ABC132Acd March 14, 2012 9:06 am 

    As a rat lover? and caregiver I love your little PSA in this video about the dangers of giving rats sacron.

  17. hollowaynz1 March 14, 2012 8:17 am 

    Any idea of a diet cola that’s AceK-free then? It seems that Diet Coke and Coke Zero? have it.

  18. Kostly March 14, 2012 7:37 am 

    @wjestick We don’t consume snake? venom and poison frogs everyday, do we?

  19. cyberaquarius March 14, 2012 7:31 am 

    -Abhilash M et al., “Effect of long term intake of aspartame on antioxidant defense status in liver.” Food Chem Toxicol. 2011? Jun;49(6):1203-7. Epub 2011 Mar 3.
    -Ciappuccini R et al., “Aspartame-induced fibromyalgia, an unusual but curable cause of chronic pain.” Clin Exp Rheumatol. 2010 Nov-Dec;28(6 Suppl 63):S131-3. Epub 2010 Dec 22.
    -Soffritti M et al., “Aspartame administered in feed, beginning prenatally through life span, induces cancers of the liver and lung in male Swiss mice.”

  20. cyberaquarius March 14, 2012 7:13 am 

    -Walton RG et al., “Adverse reactions to aspartame: double-blind challenge in patients from? a vulnerable population.” Biol Psychiatry. 1993 Jul 1-15;34(1-2):13-7
    -Van den Eeden SK et al., “Aspartame ingestion and headaches: a randomized crossover trial.” Neurology. 1994 Oct;44(10):1787-93.

  21. cyberaquarius March 14, 2012 6:44 am 

    -Walton RG et al., “Adverse reactions to aspartame: double-blind challenge in patients from a vulnerable population.” Biol? Psychiatry. 1993 Jul 1-15;34(1-2):13-7
    -Van den Eeden SK et al., “Aspartame ingestion and headaches: a randomized crossover trial.” Neurology. 1994 Oct;44(10):1787-93.

  22. adolson March 14, 2012 5:54 am 

    I’ve had no? issues with Xylitol, and I’ve been eating it for years.

  23. mphello March 14, 2012 5:25 am 

    Examples like saccharin only support the political case for banning animal testing on vertebrates or “higher”: humans don’t deserve the benefits of knowledge gained by torturing animals in labs.

    All my disagreements with scientists are moral/ethical, not with the? science.

  24. Kuroneko388 March 14, 2012 4:29 am 

    My advice to you ppl would be to try Stevia. It’s sweeter than sugar and none? of the bad side effects like diabetes and cavities.

  25. isrealjason March 14, 2012 4:16 am 

    thanks for the vid’s but do you think it is time to leave youtube for a dif site?i’m down?

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